Madonna and Child with Angels and Saints Jerome, Catherine of Alexandria, Lucy and John the Evangelist

Siena fell in April 1555, after a long siege by the troops of Emperor Charles V and his Florentine allies, and according to the usual account Spanish soldiers took this altarpiece during that war. It had most likely been painted around 1513 for Sigismondo Chigi, brother of the Roman banker Agostino Chigi, for the church of San Bartolomeo near the family villa at Le Volte, just outside Siena. Afterwards it turned up in a church at Colle di Val d'Elsa, probably Santa Caterina. By 1825 it was for sale in Florence, and around 1840 the royal gallery in Turin, then directed by Roberto d'Azeglio, bought it from the Florentine Rosselli del Turco family.

Its date has wandered. In the 19th century it was taken for an early work, and in 1906 the English biographer Robert Cust moved it to the late 1530s. The date accepted today, around 1513, rests on its closeness to an altarpiece of the mystic marriage of Saint Catherine that the Florentine friar Fra Bartolomeo finished in 1512 for the church of San Marco.